Carbohydrate-based first stereoselective total synthesis of bioactive cytospolide P.
نویسندگان
چکیده
A facile carbohydrate-based highly stereoselective synthetic route has been developed for the cytospolide P (1) from D-ribose for the first time. Key steps of the synthesis include Wittig homologation, regioselective epoxide ring opening, Sharpless asymmetric epoxidation, Evans aldol reaction, and Yamaguchi macrolactonization.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 21 شماره
صفحات -
تاریخ انتشار 2014